Mechanisms and Mediators of Neuropathic Pain (Progress in Inflammation Research) (Hardcover)

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Mechanisms and Mediators of Neuropathic Pain (Progress in Inflammation Research) (Hardcover)

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Numerous improvements in our understanding of the mechanisms that underlie neuropathic pain states have come from the development of animal models, most of which involve partial peripheral nerve injury. The animal models have shown that nerve injury initiates a cascade of events resulting in altered neurochemistry and molecular biology of the peripheral neurons, the dorsal root ganglion cell, and changes in neurotransmitter and receptor expression in the dorsal horn of the spinal cord. Moreover, nerve injury produces anatomical changes with functional consequences.
This volume summarises the current understanding of the pathophysiological processes in the peripheral and central nervous system that contribute to the neuropathic pain. It provides a timely review of neuropathic pain mechanisms, written by experts in the field.

Product Details ISBN: 9783764362379
ISBN-10: 3764362375
Publisher: Birkhauser
Publication Date: April 1st, 2002
Pages: 260
Language: English
Series: Progress in Inflammation Research